Cell, Tumor, and Stem Cell Biology Acyl-CoA Synthetase VL3 Knockdown Inhibits Human Glioma Cell Proliferation and Tumorigenicity
نویسندگان
چکیده
Gene Expression Profiles in Peripheral Blood Mononuclear Cells Can Distinguish Patients with Non–Small Cell Lung Cancer from Patients with Nonmalignant Lung Disease. Michael K. Showe, Anil Vachani, Andrew V. Kossenkov, Malik Yousef, Calen Nichols, Elena V. Nikonova, Celia Chang, John Kucharczuk, Bao Tran, Elliot Wakeam, Ting An Yie, David Speicher, William N. Rom, Steven Albelda, and Louise C. Showe ................................................9202
منابع مشابه
Acyl-CoA synthetase VL3 knockdown inhibits human glioma cell proliferation and tumorigenicity.
The contribution of lipid metabolic pathways to malignancy is poorly understood. Expression of the fatty acyl-CoA synthetase ACSVL3 was found to be markedly elevated in clinical malignant glioma specimens but nearly undetectable in normal glia. ACSVL3 levels correlated with the malignant behavior of human glioma cell lines and glioma cells propagated as xenografts. ACSVL3 expression was induced...
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